Description
The Comprehensive Neurotransmitters Profile (FMV/Random) is an advanced urinary test that provides a detailed assessment of the body’s ability to synthesize, secrete, and metabolize key neurotransmitters and their metabolites. This non-invasive spot urine (random/FMV) collection evaluates a broad panel of excitatory, inhibitory, and modulatory neurotransmitters, offering valuable insights into whole-body neurotransmitter balance — including contributions from the central and peripheral nervous systems as well as the gastrointestinal microbiome.
Analytes Include:Serotonin, Dopamine, Norepinephrine, Epinephrine, GABA, Glutamate, Glycine, Taurine, Histamine
Metabolites: 5-HIAA, DOPAC, 3-MT, Metanephrine, Normetanephrine
Additional markers: Phenethylamine (PEA), Tryptamine, Tyramine, Tyrosine, and more
Useful for evaluating symptoms such as:
- Evaluate the neurotransmitter portion of the NEI Supersystem
- Vasomotor Dysfunction
- Mood concerns (depression, anxiety)
- Fatigue and low energy
- Insomnia and sleep disturbances
- Cognitive issues (brain fog, inattention, forgetfulness)
- Cravings, addictions, and obsessions
- Chronic pain, low libido, and immune-related challenges
By identifying imbalances in neurotransmitter metabolism — influenced by nutrition, genetics, stress, inflammation, and environmental factors — this profile supports targeted interventions to improve clinical outcomes. A 24-hour urine collection is recommended if kidney function is compromised.Ideal for functional and integrative practitioners seeking deeper insight into mood, cognition, behavior, and overall neurological health.
Analytes tested:
- 3,4-Dihydroxyphenylacetic acid (DOPAC)
- 3-Methoxytyramine (3-MT)
- 5-Hydroxyindolacetic acid (5-HIAA)
- Catecholamine Fractionation, free
- Creatinine
- Dopamine, free
- Epinephrine, free
- Gamma-aminobutyrate
- Glutamate
- Glycine
- Histamine
- Metanephrine Fractionation
- Metanephrine
- Norepinephrine, free
- Normetanephrine
- Phenethylamine (PEA)
- Serotonin
- Taurine
- Tryptamine
- Tyramine
- Tyrosine







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