Description
The Comprehensive Neurotransmitters Profile (24-hr Urine) from Doctor’s Data delivers an advanced, in-depth assessment of neurotransmitter secretion and metabolism. This extensive 24-hour urine test evaluates a broad panel of key neurotransmitters and their metabolites—including serotonin, dopamine, norepinephrine, epinephrine, GABA, glutamate, glycine, histamine, PEA, 5-HIAA, DOPAC, metanephrines, and more—providing a comprehensive view of the body’s ability to synthesize and break down these essential chemical messengers.
Urinary neurotransmitter levels reflect whole-body production across the central and peripheral nervous systems as well as the gastrointestinal microbiome. This profile is particularly valuable for evaluating the neurotransmitter portion of the NEI Supersystem (Neurological-Endocrine-Immune), assessing vasomotor dysfunction, providing functional testing insights related to COMT and MAOA enzyme activity, identifying neurological imbalances, measuring response to therapy, and supporting overall risk assessment.
Practitioners use this test to investigate symptoms such as mood disorders (depression, anxiety), fatigue, insomnia, cognitive issues (brain fog, inattention), cravings/addictions, chronic pain, and low libido. The 24-hour collection offers a more stable and representative assessment of daily excretion, especially recommended when renal function may be compromised. Results deliver actionable insights that guide targeted nutritional, lifestyle, and supplementation strategies to restore balance and improve patient outcomes.
This test is useful for:
- Evaluate the neurotransmitter portion of the NEI Supersystem
- Vasomotor Dysfunction
- testing for COMT and MAOA
- Identifying neurological imbalances
- Measuring response to therapy
- Risk assessment
Analytes tested:
- 3,4-Dihydroxyphenylacetic acid (DOPAC)
- 3-Methoxytyramine (3-MT)
- 5-Hydroxyindolacetic acid (5-HIAA)
- Catecholamine Fractionation, free
- Creatinine
- Dopamine, free
- Epinephrine, free
- Gamma-aminobutyrate
- Glutamate
- Glycine
- Histamine
- Metanephrine Fractionation
- Metanephrine
- Norepinephrine, free
- Normetanephrine
- Phenethylamine (PEA)
- Serotonin
- Taurine
- Tryptamine
- Tyramine
- Tyrosine
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