Discover Adrenal Stress Index Zone 1 – Stress adapted ‘Hyper Response,’ marking the initial acute response to stress and the onset of the alarm reaction. Common in overworked individuals and athletes overtraining, this stage typically resolves with stress removal. Explore protocols to improve performance, mitigate physiological impacts, and prevent adrenal progression to resistance or exhaustion stages. Take proactive steps to maintain well-being and optimize adrenal health.
Zone 1. Stress adapted “Hyper Response”
Zone 1 signifies the initial and acute reaction to stress, marking the onset of the alarm reaction. This pattern is commonly observed in healthy individuals who push themselves beyond limits or in athletes engaging in excessive training. Typically, this stage resolves spontaneously once the stressor is eliminated. However, if the individual persists in facing stressors or refuses to reduce their training intensity, it’s essential to consider specific protocols. These protocols aim to enhance performance, mitigate adverse physiological effects, and halt further progression of adrenal dysfunction towards the resistance or exhaustion stage.
Recommendation for Supplementation:
- Glysen (K-1):
- Protoglysen (K-28)
- Adaptacrine (K-2):
- Adrenacalm-SE (K-73):
- Omega CO-3 (K-7):
- Brain-E DHA (CF) (K-55):
Adrenal Stress Index
- Use Cortisol/DHEA ratios to guide treatment.
- Stay on protocol until next test, monitor progress of protocol at 30 day intervals with MAF.
- If there is improvement in Cortisol/DHEA Zone on the ASI, alter supplementation protocol to new zone.
- Retest ASI in six to eight weeks.
- ASI Test Component factors may indicate additional supplementation, dietary changes and/or testing.
Adrenal Deal Breaker
Anemia
If you are anemic. You should order Bio-Screen Sustain Max to determine which type of anemia causing your symptoms.
It is very difficult to improve adrenal/blood sugar patterns if the patient is anemic. Your Red blood Cells will not be able to deliver oxygen to mitochondria for ATP production and will be dependent upon glycolosis for energy production. Glycolosis is very inefficient and places great demands upon the blood sugar/adrenal stabilizing system.
Inflammation/Unresolving Immune Response
If your anemia is due to inflammation and/or bacterial infection use of iron supplements will increase bacterial growth, free radical production and an unresolving immune response. Do Not Use Iron Supplements in presence of inflammation.
Adrenal Stress Index Zone 1 Support Products

Apex Energetics Glysen K-2
$32.98 – $51.98
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Apex Energetics Glysen-Synergy K-79
$89.98
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Apex Energetics Adaptacrine K-2
$39.98 – $45.98
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Apex Energetics AdrenaCalm KR-16
$45.98
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Apex Energetics OmegaCo-3 16 oz. K-7
$27.98
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Apex Energetics OmegaCo-3-SE K-113 90 Softgel
$36.98
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Apex Energetics Protoglysen K-28
$38.50
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Apex Energetics Brain-E DHA 4oz. K-53
$56.98
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Apex Energetics Phyto Brain-E 4oz. K-54
$85.79
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Apex Energetics Phyto Brain-E XL 8oz. K-123
$157.79
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Adrenal Stress Index Zones:
- Adrenal Stress Index Optimal Zone
- Adrenal Stress Index Zone 1
- Adrenal Stress Index Zone 2
- Adrenal Stress Index Zone 3
- Adrenal Stress Index Zone 4
- Adrenal Stress Index Zone 5
- Adrenal Stress Index Zone 6
- Adrenal Stress Index Zone 7
Related Keywords:
- Cortisol levels
- Adrenal fatigue
- Adrenal gland function
- Stress and adrenal health
- Adrenal support supplements
- hpt axis
- hypothalamic pituitary adrenal axis
- adrenal stress index
Top Competitor Sites with URLs:
- Healthline – https://www.healthline.com/
- Mayo Clinic – https://www.mayoclinic.org/
- WebMD – https://www.webmd.com/
Suggested Sites for Outreach and Backlinks:
- Harvard Health Publishing – https://www.health.harvard.edu/
- National Institutes of Health (NIH) – https://www.nih.gov/
- American Institute of Stress – https://www.stress.org/