Unlock insights into Adrenal Stress Index Zone 5 – a stage indicating the onset of adrenal fatigue. Discover how suppressed cortisol levels and normal-range DHEA levels signify the adrenals’ struggle to adapt to stress. Learn about the implications of compromised cortisol and DHEA production as stress persists. Take proactive steps to support adrenal health and combat adrenal fatigue.
Zone 5. Non-adapted, Adrenal Fatigue
This pattern demonstrates the onset of the adrenal exhaustion stage. The levels of Cortisol are suppressed. The DHEA levels are in the normal range due to the adrenals inability to adapt to stress and shift pregnenolone into Cortisol. As the stress continues, the adrenal ability to produce Cortisol and DHEA will become compromised.
Recommendation for Supplementation:
1. Proglyco-SP:
2. Adaptacrine:
3. Adrenastim:
4. Super EFA complex (K-8):
Phase 1. Restoration Plan
Adrenal Stress Index
A. Use Cortisol/DHEA ratios to guide treatment.
i. Stay on protocol until next test, monitor progress of protocol at 30 day intervals with MAF.
ii. If there is improvement in Cortisol/DHEA Zone on the ASI, alter supplementation protocol to new zone.
iii. If there is little or no change remain on protocol until there is a change in their symptoms, either expressed verbally or noted on MAF.
iv. If there is concurrent depressed SIgA levels and Insulin Resistance consider completing the Metabolic Reset.
B. Retest ASI in six to eight weeks.
Adrenal Deal Breakers

- Portal Hypertension: The Hidden Vascular Burden
- Adrenal Uncoupling: Mitochondrial Chaos
- Anemia: The Oxygen Deficit No One Talks About
- Insulin Resistance: The Endocrine Saboteur
- Low Cholesterol: The Steroid Precursor Deficiency
- Non-Resolving Immune Responses: The Fire That Won’t Go Out
- Splanchnoptosis: The Fallen Organs Syndrome
- Surgical Menopause: Hormonal Shockwave
- Dehydration: The Forgotten Stressor
- Adhesions: Fascia that Chokes the Flow
- Chronic SSRI Usage: Flattened Stress Response
- Emotional Stress: The Trigger and the Fuel
- Autoimmune Conditions: Self-Attack on Endocrine Tissue
- Heavy Metals & DMT1 Upregulation: The Inflammatory Loop
- Environmental Antigen Burden: Modern Toxicity Overload
Adrenal Rehabilitation Support Products
Adrenal Stress Index Zones:
- Adrenal Fatigue Deal Breakers
- Adrenal Stress Index Optimal Zone
- Adrenal Stress Index Zone 1
- Adrenal Stress Index Zone 2
- Adrenal Stress Index Zone 3
- Adrenal Stress Index Zone 4
- Adrenal Stress Index Zone 5
- Adrenal Stress Index Zone 6
- Adrenal Stress Index Zone 7
Related Keywords:
- Cortisol levels
- Adrenal fatigue
- Adrenal gland function
- Stress and adrenal health
- Adrenal support supplements
- hpt axis
- hypothalamic pituitary adrenal axis
- adrenal stress index
Top Competitor Sites with URLs:
- Healthline – https://www.healthline.com/
- Mayo Clinic – https://www.mayoclinic.org/
- WebMD – https://www.webmd.com/
Suggested Sites for Outreach and Backlinks:
- Harvard Health Publishing – https://www.health.harvard.edu/
- National Institutes of Health (NIH) – https://www.nih.gov/
- American Institute of Stress – https://www.stress.org/